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But too much iron — or problems with utilizing, storing, or transporting iron properly — can lead to vision loss in the form of conditions such as age-related macular degeneration and hyperferritinemia syndrome, according to recent research findings. Age-related macular degeneration AMD is regarded as the leading cause of vision loss for people over the age of The macula, a small portion of the retina which is responsible for sharp and detailed vision, deteriorates over time when the retinal pigment epithelium RPE surrounding the macula oxidizes — triggering an inflammatory response. Iron chelation therapy is the removal of excess iron from the body with special drugs. Oftentimes the storage protein for iron, ferritin, can reach the eye instead of the mineral itself. The result is hereditary hyperferritinemia cataract syndrome HHCS , an inherited condition of early-onset cataracts which could be dangerously confused with hemochromatosis iron overload unless a person is diagnosed using the full iron panel:
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